97% Proteins Preserved2
- Growth Factors
- Hyaluronic Acid (HA)
Exosomes can deliver
these signals 3,4,5
- Immune Priviledge
Isolating the beneficial signals given out by stem cells and using them rather than the stem cells themselves are the next generation as a therapy. This makes sense, as other cells react to these signals and change their behavior accordingly. There is a tremendous therapeutic potential of extracellular vesicles, particularly exosomes.
Maximum Safety & Quality in Every Batch
- Sterile-filtered without radiation
- No cryoprotectant or dilutants ever used
- Endotoxin and USP <71> testing on all lots
- Non Expanded/Non Cultured
- 100% pure liquid allogenic secretion
- Maximum bioavailability
- Non-nucleated cell
- Minimal Manipulated
ACELLULAR - STERILE FILTERED
Quality Compliance & Donor Screening
- Donor consent prior to collections
- HCV (Hepatitis C Antibody)
- HBsAG (Hepatitis B Surface Antigen)
- HIV 1/11-Ab (HIV Nucleic Acid Test)
- HBcAb (Hepatitis B core Antibody)
- HCV NAt (HCV Nucleic Acid Test)
Exosomes are cell-derived nanoparti-cles that play a pivotal role in cell-to-cell communication and are involved in a wide range of physiologi-cal processes. They have an impor-tant role in the transfer of proteins, mRNA, miRNA and other bioactive molecules between cells and regulate gene expression in recipient cells, thus influencing various molecular path-ways.
CLINICAL SUPPORT & ORDERING INFORMATION
1. (Quantitative enzyme-linked immunosorbent assay) Pierce et al. Collection and characterization of amniotic fluid from scheduled C-section deliveries. Cell and Tissue Banking; 2016 17: 413.
2. (Post-processing characterization of amniotic fluid) Pierce et al. Collection and characterization of amniotic fluid from scheduled C-section deliveries. Cell and Tissue Banking; 2016 17: 413.
3. Burrello, J., et al. (2016). “Stem Cell-Derived Extracellular Vesicles and Immune-Modulation.” Front Cell Dev Biol 4: 83.
4. Kishore, R. and M. Khan (2016). “More Than Tiny Sacks: Stem Cell Exosomes as Cell-Free Modality for Cardiac Repair.” Circ Res 118(2): 330-343.
5. Kishore, R. and M. Khan (2016). “More Than Tiny Sacks: Stem Cell Exosomes as Cell-Free Modality for Cardiac Repair.” Circ Res 118(2): 330-343.
6. Reems J. “Amniotic fluid: Thicker than water.” Perinatal Stem Cell Society Congress, 2 March 2018, The Leonard Museum, Salt Lake City, UT
7. Thery Clotilde, “Exosome Explosion” The Scientist, 2011, www.the-scientist.com/?articles.view/articleNo/30793/title/Exosome-Explosioni.html