Organicell™ Flow

exosomes therapeutics

97% Proteins Preserved2

Components of
Organicell™ Flow

  • Exosomes
  • Cytokines
  • Chemokines
  • Growth Factors
  • Hyaluronic Acid (HA)

Exosomes can deliver
these signals 3,4,5

  • Anti-Apoptotic
  • Anti-Fibrotic
  • Pro-Angiogenic
  • Pro-Differentiation
  • Pro-Proliferation
  • Immunomodulatory
  • Immune Priviledge

Isolating the beneficial signals given out by stem cells and using them rather than the stem cells themselves are the next generation as a therapy. This makes sense, as other cells react to these signals and change their behavior accordingly. There is a tremendous therapeutic potential of extracellular vesicles, particularly exosomes.

Maximum Safety & Quality in Every Batch

  • Sterile-filtered without radiation
  • No cryoprotectant or dilutants ever used
  • Endotoxin and USP <71> testing on all lots
  • Non Expanded/Non Cultured¬†
  • 100% pure liquid allogenic secretion
  • Maximum bioavailability
  • Non-nucleated cell
  • Minimal Manipulated

Exosome Validation

Organicell™ Flow contains approximately 400 billion exosomes per milliliter. Exosomes are nanovesicles that contain protein and RNA and can be transferred to other cells and may support tissue repair and homeostasis.6.7

exosomes therapeutics

ACELLULAR - STERILE FILTERED

Quality Compliance & Donor Screening

Organicell™ Flow is procured and processed in the United States according to standards and regulations established by the American Association of Tissue Banks (AATB), the United States Food & Drug Administration (FDA). All local donors. Donor ethics and non-reactive FDA approved serological screening includes:
  • Donor consent prior to collections
  • HCV (Hepatitis C Antibody)
  • HBsAG (Hepatitis B Surface Antigen)
  • HIV 1/11-Ab (HIV Nucleic Acid Test)
  • HBcAb (Hepatitis B core Antibody)
  • HCV NAt (HCV Nucleic Acid Test)

organicell
flowTM

Product Offering

Item Number:Size
100F011 cc

Exosomes

Exosomes are cell-derived nanoparti-cles that play a pivotal role in cell-to-cell communication and are involved in a wide range of physiologi-cal processes. They have an impor-tant role in the transfer of proteins, mRNA, miRNA and other bioactive molecules between cells and regulate gene expression in recipient cells, thus influencing various molecular path-ways. 

CLINICAL SUPPORT & ORDERING INFORMATION

CUSTOMER SERVICE 1.888.963.7881 EMAIL US info@organicell.com

REFERENCES

1. (Quantitative enzyme-linked immunosorbent assay) Pierce et al. Collection and characterization of amniotic fluid from scheduled C-section deliveries. Cell and Tissue Banking; 2016 17: 413.

2. (Post-processing characterization of amniotic fluid) Pierce et al. Collection and characterization of amniotic fluid from scheduled C-section deliveries. Cell and Tissue Banking; 2016 17: 413.

3. Burrello, J., et al. (2016). “Stem Cell-Derived Extracellular Vesicles and Immune-Modulation.” Front Cell Dev Biol 4: 83.

4. Kishore, R. and M. Khan (2016). “More Than Tiny Sacks: Stem Cell Exosomes as Cell-Free Modality for Cardiac Repair.” Circ Res 118(2): 330-343.

5. Kishore, R. and M. Khan (2016). “More Than Tiny Sacks: Stem Cell Exosomes as Cell-Free Modality for Cardiac Repair.” Circ Res 118(2): 330-343.

6. Reems J. “Amniotic fluid: Thicker than water.” Perinatal Stem Cell Society Congress, 2 March 2018, The Leonard Museum, Salt Lake City, UT

7. Thery Clotilde, “Exosome Explosion” The Scientist, 2011, www.the-scientist.com/?articles.view/articleNo/30793/title/Exosome-Explosioni.html